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Main smoothLRC algorithm

Usage

smooth_model(x, u_init, v_init, w, index, lambda, epsilon, maxiter)

Arguments

x

sparse matrix; assay matrix

u_init

matrix; u initialization matrix

v_init

matrix; v initialization matrix

w

matrix; distance matrix. If null, computed to specification with k nearest neighbors.

index

w indicies.

lambda

positive numeric; penalization parameter.

epsilon

positive numeric; convergence criterion.

maxiter

positive integer; maximum desired iterations

Value

SummarizedExperiment object with u, v and cluster labels.

Examples


sce <- example_sce()
x <- SummarizedExperiment::assay(sce)
coords <- SummarizedExperiment::colData(sce)[, c("col", "row")]
k <- 10
init <- smooth_init(x, coords, k)
lambda <- 1
epsilon <- 1e-3
maxiter <- 5
smooth_model(x, init$u0, init$v0, init$w, init$index, lambda, epsilon, maxiter)
#> iteration: 1 | convergence: 0.106201 | 0.0371337 | 1
#> iteration: 2 | convergence: 0.0903484 | 0.0311731 | 0.00525504
#> iteration: 3 | convergence: 0.0870562 | 0.0367362 | 0.00560428
#> iteration: 4 | convergence: 0.0876035 | 0.0403189 | 0.00625686
#> iteration: 5 | convergence: 0.0890037 | 0.0420041 | 0.0071044
#> $u
#>                  [,1]          [,2]          [,3]          [,4]          [,5]
#>    [1,]  0.2007066735  8.865972e-02 -0.0671240212  0.0221808448 -0.3089801298
#>    [2,]  0.0068779493  4.225074e-02  0.0634413733  0.0059770036 -0.0051897911
#>    [3,]  0.1474356856  3.878247e-02  0.3524605550  0.2631222898  0.0083108161
#>    [4,]  0.1758078569  7.641218e-02 -0.0994096059  0.0392977980 -0.0755143651
#>    [5,]  0.0523636971  5.986077e-02  0.0098076570  0.0304484059 -0.0348481628
#>    [6,]  0.1442057406  1.416731e-01  0.3133375466  0.1137707557  0.1003648849
#>    [7,]  0.0532971171  4.387710e-02 -0.0863071615  0.0754363119 -0.0814809179
#>    [8,]  0.2205740278  3.011001e-01  0.0490613055 -0.3482692322 -0.1070543084
#>    [9,]  0.0746570395  5.414608e-02 -0.1160163893  0.0591123971  0.0629343738
#>   [10,]  0.0106591946  3.037733e-02 -0.0576274600  0.0576634995 -0.0239671931
#>   [11,]  0.0734189036  1.813488e-02 -0.1137814347  0.0093114216  0.0376100823
#>   [12,]  0.0789922001  1.507262e-02 -0.1302131670  0.0274423331 -0.0010450493
#>   [13,]  0.0612681065  3.513416e-03  0.0265970617 -0.1501539770 -0.0597147888
#>   [14,]  0.1937663701  2.341532e-02  0.1456436556 -0.1878269022 -0.0366633205
#>   [15,]  0.1065638279  1.347485e-01 -0.1152510032 -0.0907983826 -0.0122281114
#>   [16,]  0.1925211758 -2.790384e-02 -0.1243203230  0.1794781533  0.1976379866
#>   [17,]  0.0333029908  1.154662e-01  0.0357108169 -0.1163251629 -0.0362815652
#>   [18,]  0.0675422292  9.447625e-02  0.1667602378  0.0658661931 -0.0162974902
#>   [19,]  0.0610069136  1.073274e-01  0.2555974145  0.1054721570  0.0167433454
#>   [20,] -0.0256668678  3.990149e-02 -0.0409612167  0.0708914994 -0.0402666261
#>   [21,]  0.1295508997  4.871966e-02  0.0757343049 -0.1185101262 -0.0313169427
#>   [22,]  0.1229994476  1.001976e-02  0.1008258802  0.0895054918 -0.0310976643
#>   [23,]  0.0045216409  3.818953e-02 -0.0948238753  0.0662675543 -0.0009356166
#>   [24,]  0.1010423838  1.497169e-01  0.0601373379 -0.2851338137 -0.0511941482
#>   [25,]  0.0605055328  1.475781e-01  0.0376472791  0.0259878629 -0.0164971186
#>   [26,] -0.0151799690  9.034042e-02 -0.0617189230  0.0561316178  0.0042896253
#>   [27,]  0.0867396688  1.207830e-01 -0.0333724719  0.0655977713 -0.0461601368
#>   [28,]  0.1170477000 -5.921024e-02 -0.0570784354  0.0254073965  0.1987673309
#>   [29,]  0.1098341952  1.357562e-01 -0.1061515406 -0.1612299855  0.0160733449
#>   [30,] -0.0035738690  3.522324e-02 -0.0221909269 -0.0082103036 -0.0123589763
#>   [31,]  0.2603915083 -8.218033e-02 -0.1273625625  0.2449432940  0.2583705736
#>   [32,]  0.0168444599  5.903458e-02 -0.0148333523  0.0328390465  0.0081771004
#>   [33,]  0.0291858334  4.754408e-02  0.0115379053  0.0256341993  0.0266797942
#>   [34,]  0.0082246248  5.921923e-02  0.0723520957  0.0205583231 -0.0504449555
#>   [35,]  0.0538666178  1.505109e-02 -0.0687611900 -0.0007870401  0.0310764628
#>   [36,] -0.0210291773  6.749544e-02 -0.0227602559  0.0277247774 -0.0090546807
#>   [37,]  0.1890950618 -1.549371e-01  0.1395826214  0.1159481212 -0.1623220098
#>   [38,]  0.0792824202 -2.090137e-02  0.0052084003  0.0992171516 -0.2573076918
#>   [39,]  0.0252860294  5.100394e-02  0.0306379392  0.0190346581 -0.0364963579
#>   [40,]  0.0472026974  1.690404e-02  0.1980241203  0.1943563565 -0.0325927848
#>   [41,]  0.1384828110 -3.427575e-02  0.0022426605  0.0356678836 -0.1759588872
#>   [42,] -0.0031611172  9.505073e-02 -0.0297923511  0.0649329683 -0.0012840483
#>   [43,]  0.2563036641 -4.689148e-01 -0.2009638709  0.0979694737  0.0073417811
#>   [44,]  0.1162037849  1.833571e-01 -0.1439317651  0.0698613063 -0.0308369964
#>   [45,]  0.0064284386  7.864658e-02 -0.1086020661  0.0548502460 -0.0496703852
#>   [46,]  0.0725679327  7.660213e-02 -0.0158569175  0.1188521489 -0.0292352646
#>   [47,]  0.1479485089 -3.704375e-02 -0.1071841346  0.0599274149 -0.1389458756
#>   [48,]  0.0780417763  1.216165e-01 -0.1163015976  0.1888882950  0.0124732687
#>   [49,]  0.1104965723  3.082087e-02 -0.0683676104 -0.0416542627 -0.0922662861
#>   [50,]  0.0861975576 -2.096414e-02  0.0055342590 -0.0966823289 -0.1073734990
#>   [51,]  0.0552893731  7.545413e-02 -0.0829414015  0.0290662754  0.0950316026
#>   [52,]  0.0570641393  1.238584e-01 -0.0963074105  0.0467455776 -0.0509507345
#>   [53,] -0.0047869770  2.336536e-02 -0.0452590659  0.0588493087 -0.0442220726
#>   [54,]  0.0321476410  4.344545e-03 -0.1072919723  0.0446683501 -0.0438232449
#>   [55,]  0.0404498762  7.025164e-02  0.0986229655  0.0243401407 -0.0493128627
#>   [56,] -0.0188884364  3.485793e-02 -0.0633120663  0.0516649375 -0.0305288684
#>   [57,]  0.1438942261 -2.922097e-01 -0.2487522278  0.1878343368  0.0880538835
#>   [58,]  0.0091004708  2.723583e-02 -0.0569561706  0.0664620846 -0.0208367770
#>   [59,]  0.0881333636  9.354251e-02  0.0058170309  0.0429191698  0.0710920385
#>   [60,]  0.1126481808  1.879270e-02  0.0831718915  0.3164338063 -0.0537747504
#>   [61,]  0.0387658504 -9.413197e-03 -0.0710769728 -0.0651831050 -0.0256980641
#>   [62,]  0.0889589125 -5.139547e-02 -0.0703897367 -0.0604056034 -0.0596675990
#>   [63,]  0.1678009465 -1.177955e-02 -0.0443380833 -0.2011215064 -0.0994761493
#>   [64,]  0.1151844934 -3.067110e-02  0.2492941582 -0.1375567204 -0.0624134264
#>   [65,]  0.0244754667  1.735743e-02 -0.0350143719  0.0796422503 -0.0330602176
#>   [66,]  0.1056211361  4.834840e-02  0.0506117875  0.0814127630  0.0657425919
#>   [67,]  0.0401060086  2.372619e-02 -0.0657800635 -0.0371657376  0.0461537892
#>   [68,]  0.0303080907  1.027638e-01  0.0413353841  0.0100017463 -0.0151455793
#>   [69,]  0.1147273315  2.143274e-01 -0.1383956209  0.0398317935  0.0580743442
#>   [70,]  0.0224416041  3.709760e-02  0.0131977328 -0.1139083689 -0.0268965336
#>   [71,]  0.0372539557  6.624342e-02 -0.0142656288 -0.1048656592 -0.0549175282
#>   [72,]  0.2416317360  3.027947e-01 -0.0809408230  0.1453269456  0.0310899091
#>   [73,]  0.0415510289  3.147302e-02  0.0160845051 -0.0984404385 -0.1100811349
#>   [74,]  0.1867250409 -2.039713e-01  0.1228426297  0.0890582923 -0.2283637017
#>   [75,]  0.0281007989 -1.294362e-02 -0.0665732715  0.0623690218 -0.0491946894
#>   [76,]  0.2124574120  1.284490e-01  0.1546760809  0.2458556387 -0.1314332438
#>   [77,]  0.1170150274  4.374834e-02 -0.0698689896 -0.0770929413  0.0197378109
#>   [78,]  0.1496022375  1.203048e-01  0.0930899996  0.1297441365 -0.2636931190
#>   [79,]  0.0383910007  1.395806e-01  0.1708355939  0.1079151463  0.0389262885
#>   [80,]  0.0475253807 -2.097583e-02  0.1505831601  0.0316147923  0.0245105832
#>   [81,]  0.1206395620 -1.463422e-01 -0.1088588030 -0.0470422781  0.0154885425
#>   [82,] -0.0331112575  1.630393e-02  0.0034341302  0.0425238146 -0.0325672418
#>   [83,]  0.1774825031  1.987985e-01 -0.0212239187  0.1796320754  0.0291993305
#>   [84,]  0.0991928015  6.892928e-02  0.0062164983  0.0312663157  0.0215914195
#>   [85,]  0.0447199794  7.454482e-02 -0.1255961428  0.0636132262  0.0691665125
#>   [86,]  0.0328986092 -2.332612e-02  0.1180202524  0.1494714557 -0.0556888092
#>   [87,]  0.1529226087  5.017280e-02 -0.1887237306  0.0548737319 -0.0512544022
#>   [88,]  0.1729656718  1.180506e-01  0.1499932557  0.0411830573 -0.0681602828
#>   [89,]  0.2621162536 -5.000792e-01 -0.1106533400 -0.2152392859  0.0013071658
#>   [90,]  0.1535433038  1.572316e-01 -0.0942827752  0.0516211273 -0.0963399642
#>   [91,]  0.1195379493  7.183507e-02 -0.0745787403  0.1934899467 -0.0692007911
#>   [92,]  0.0140816701 -3.118873e-02 -0.0332242656  0.0166702593 -0.0371422785
#>   [93,]  0.1111031164  3.210763e-02 -0.1593914109  0.0013792903  0.0275452972
#>   [94,]  0.0634513237  8.022598e-02 -0.0993934927  0.0596453752  0.0882019987
#>   [95,]  0.0575641990  5.256782e-02 -0.1216738017 -0.1150217454  0.1046296464
#>   [96,]  0.1154559521  2.719382e-01  0.1449791775 -0.2147402383 -0.0467345114
#>   [97,]  0.0888308958 -1.219501e-01  0.0233159236  0.0238150619 -0.0410215206
#>   [98,]  0.0145436194  5.322205e-02  0.0425575130  0.0685137711  0.0298201816
#>   [99,]  0.1295013915 -6.433418e-02 -0.1916729790  0.1399459422  0.1570209984
#>  [100,]  0.0458464909  1.155659e-02 -0.0196672297 -0.0096317892 -0.1274901282
#>                 [,6]          [,7]          [,8]          [,9]         [,10]
#>    [1,]  0.208176331 -0.4244605407 -0.1619187888  0.0493685146  1.579639e-01
#>    [2,]  0.022628988 -0.0482215840  0.0392023634  0.0850043012  4.986152e-02
#>    [3,]  0.013176348  0.0328130149 -0.1097599359  0.1661078603  5.372837e-02
#>    [4,] -0.018397104 -0.3434033499 -0.2987413563 -0.1057473747 -1.285573e-02
#>    [5,]  0.059126072  0.0910942357 -0.0435812612  0.0783955045 -9.985797e-03
#>    [6,]  0.097532640  0.1930207003 -0.0379461082  0.1969013801  2.720401e-01
#>    [7,]  0.061465838  0.0743903522 -0.0353751456 -0.0754749343  1.566203e-02
#>    [8,]  0.080783375  0.0357875574 -0.3653210065 -0.0044682710  5.350230e-02
#>    [9,] -0.030165658  0.0879251969 -0.0696500587  0.0140491269 -5.705238e-02
#>   [10,]  0.110955589  0.0691715212 -0.0466325887 -0.0422039952 -9.962702e-02
#>   [11,]  0.094739339 -0.0432288019 -0.1064740491  0.0370479313 -3.840687e-03
#>   [12,]  0.161758560  0.1314541297 -0.0683662313  0.0273256807 -3.181473e-02
#>   [13,]  0.051407686  0.1031704491  0.1543568298  0.1388908789 -7.203436e-04
#>   [14,] -0.045625988  0.0996786724 -0.0066474949  0.1607933154  2.951463e-02
#>   [15,]  0.110548586  0.0529091025 -0.1110524685 -0.1014682465 -7.313268e-02
#>   [16,] -0.211690206 -0.1297453968  0.0091113458  0.1695411473 -1.184478e-02
#>   [17,]  0.183715713 -0.1167408687 -0.1533352669 -0.1095224540  9.392686e-02
#>   [18,]  0.022726447  0.1181676014 -0.1201887429  0.1025726325  5.755983e-02
#>   [19,]  0.071116190  0.1884076650  0.0251634116  0.1130796369  2.098902e-01
#>   [20,]  0.039465340  0.0126455634 -0.0563474716  0.0412239412  3.823639e-02
#>   [21,]  0.147839784  0.1147806112 -0.1210666075  0.0313981738  2.147407e-02
#>   [22,] -0.059758309  0.0696322904 -0.0017680137 -0.0498824430  2.820375e-01
#>   [23,]  0.049099396  0.0047580132 -0.0926146699  0.0036741697  2.459304e-02
#>   [24,]  0.186231397 -0.1626310548 -0.2937054169  0.0558043487  5.938487e-02
#>   [25,]  0.105874280  0.1160972520  0.0277934980  0.1218299740  1.391006e-01
#>   [26,]  0.085374701  0.0751815459 -0.0393976495  0.0578134752  6.629325e-04
#>   [27,]  0.161411169 -0.0205577328  0.0435181184  0.0199850339 -8.226140e-02
#>   [28,] -0.109466189  0.0239142936 -0.0970156849 -0.1662879840  2.921723e-02
#>   [29,] -0.109619161 -0.0551339634 -0.1346530204  0.0231836143  5.614589e-03
#>   [30,]  0.067285441 -0.0180484693 -0.1020909814  0.0014935568  6.372262e-02
#>   [31,]  0.188788253 -0.0749112020 -0.1175861988 -0.4485472861 -4.690547e-02
#>   [32,]  0.089148261  0.0637398502 -0.0039819427  0.0510979652  1.151467e-01
#>   [33,] -0.077914665  0.0876528378 -0.0493457718 -0.0291340190  7.959136e-02
#>   [34,]  0.085709356  0.0919373431  0.0242801466  0.0678066472  1.629041e-01
#>   [35,]  0.040867260  0.0552961247  0.1069108843  0.1287971075 -7.154997e-02
#>   [36,] -0.048461916  0.0806186548 -0.0899894313  0.0233954870  6.883652e-02
#>   [37,]  0.028019191 -0.5250050832 -0.1732366467  0.0979486427 -7.213828e-02
#>   [38,]  0.093240187  0.1526073426 -0.0464657864 -0.2177966328  3.411686e-02
#>   [39,]  0.062957316  0.0959364963  0.0220498249  0.0510679190  1.201799e-01
#>   [40,]  0.066308421  0.0276974485 -0.0887417370  0.0377701550  3.740978e-02
#>   [41,]  0.017592053 -0.3760306726  0.0929267817 -0.0562214915 -2.732554e-02
#>   [42,] -0.010704172  0.0492120645 -0.0941979540 -0.0486691439 -7.304380e-04
#>   [43,]  0.142774625  0.1752291069 -0.2556335775 -0.2038525245  1.965002e-01
#>   [44,]  0.032122681  0.1046700939 -0.1190775121 -0.1233854249  3.097333e-02
#>   [45,]  0.032284105  0.0740106936 -0.0278407799  0.0126585070  3.943443e-02
#>   [46,]  0.084926424  0.1558729044 -0.0829627838  0.0371797190  7.595525e-02
#>   [47,]  0.101415488  0.1955115827 -0.1505089851  0.1156619380 -7.052376e-02
#>   [48,] -0.055893946  0.0199581196  0.2102985337  0.2366544906  7.243967e-02
#>   [49,] -0.118296471 -0.0732045005 -0.0710165121  0.1320079472 -8.825296e-02
#>   [50,] -0.177257921  0.0425706282 -0.0703064361 -0.1301330588  1.087575e-01
#>   [51,] -0.003517092  0.0092585609  0.0138239696  0.0430983276 -4.077510e-04
#>   [52,]  0.033208017  0.0212280298  0.0310855027  0.1084585074  5.785034e-02
#>   [53,]  0.024575246 -0.0368760802 -0.0402375122  0.0669341338  2.022732e-02
#>   [54,]  0.136207992  0.0935482372 -0.0702770232 -0.0877565360 -1.016640e-02
#>   [55,]  0.060770488  0.0476462320  0.0887371505  0.0707682592 -5.541385e-02
#>   [56,]  0.074185002  0.0305312849 -0.0496613999  0.0240096636 -5.364790e-05
#>   [57,]  0.138870806  0.0084158113  0.0297186760  0.2210063530  2.154089e-01
#>   [58,]  0.048976837  0.0542520460 -0.0732097184  0.0201069106  7.232679e-02
#>   [59,]  0.074801675  0.1354008581 -0.1559022550  0.0009583226 -2.825072e-02
#>   [60,]  0.132141808 -0.1957834906 -0.0342797758  0.0968653761  3.177423e-02
#>   [61,] -0.136166917 -0.0091143881 -0.0578239464  0.0629451631 -1.237207e-02
#>   [62,] -0.069428151  0.0873483531  0.1131870717  0.0978109422 -5.863740e-02
#>   [63,] -0.177585908 -0.0481565336 -0.2279521737  0.1734434752  4.402363e-02
#>   [64,] -0.164015598 -0.0374658755  0.0332035893  0.1298113889  2.753941e-02
#>   [65,]  0.058900742 -0.0028157879 -0.0745807220  0.0573134765 -5.584940e-02
#>   [66,]  0.195280169  0.1767338816  0.0667018760  0.0596501579  3.519800e-02
#>   [67,] -0.067374395  0.0817759191 -0.0531172069  0.1049032653 -4.063321e-02
#>   [68,]  0.115095365  0.1060956908 -0.0085870128  0.0631923895  1.445944e-01
#>   [69,]  0.083026341 -0.0069618021  0.0094252366  0.0934708541  1.107691e-01
#>   [70,]  0.075473585  0.0003144115  0.0176762498  0.0583964234 -3.113601e-02
#>   [71,]  0.036741062 -0.0768436815 -0.1270287995  0.0726802253  4.865493e-02
#>   [72,]  0.107630362 -0.0455540484  0.0127211180  0.0646582175 -1.851277e-01
#>   [73,]  0.090981520 -0.0445829503 -0.0100775780 -0.0281960496  9.884348e-02
#>   [74,] -0.157084160 -0.3604296255 -0.1265321512 -0.1545001392  1.091936e-01
#>   [75,]  0.048468607  0.0312810231 -0.0337865907 -0.0155399955  1.471336e-02
#>   [76,]  0.184830734  0.1807541477 -0.2931806752  0.0801507714  4.271267e-02
#>   [77,]  0.134697012  0.0908029684 -0.0412413069  0.0694495939 -6.035475e-02
#>   [78,] -0.046389239  0.0299368232  0.1319093421 -0.0921905942  5.607704e-02
#>   [79,] -0.011905204  0.1625075195 -0.0718334845  0.1029744775  1.162091e-01
#>   [80,]  0.170106802  0.0524242477  0.0721909691  0.0620962307  3.998930e-02
#>   [81,]  0.186706604  0.0327082410 -0.1539707091  0.1181008444  1.591435e-01
#>   [82,]  0.090065184  0.0275427870 -0.0067536644  0.0356092341  4.033550e-02
#>   [83,] -0.176001362  0.1795017330  0.1520085964  0.2404368460  1.844633e-01
#>   [84,] -0.018750299  0.1141314299 -0.2474429173  0.0075622993  8.455163e-02
#>   [85,] -0.077659827 -0.0128479198 -0.0367031117 -0.0815153687  6.587492e-02
#>   [86,]  0.122186093 -0.0828534461 -0.0889982215  0.0363676598  4.995994e-03
#>   [87,] -0.006931496 -0.0902201640  0.0226358992 -0.2278934623  3.200014e-02
#>   [88,]  0.169108342 -0.1667514666 -0.1606780731  0.1260788089  1.709060e-02
#>   [89,]  0.060337546  0.1228745640  0.1149764035  0.2887513923  1.423535e-01
#>   [90,]  0.043276389  0.0947810704  0.2051392901  0.2120636180  6.012679e-02
#>   [91,] -0.140439750 -0.0079812843  0.2450546830  0.1205803358  1.423457e-01
#>   [92,]  0.014545082  0.0509030824 -0.0440998758  0.0613515966  5.196905e-03
#>   [93,]  0.184132302  0.1110476920  0.0037206042  0.0973691931 -2.936501e-01
#>   [94,]  0.151048221  0.0082513143  0.1084265301 -0.0163743472 -1.734043e-01
#>   [95,]  0.062644157  0.1343520112 -0.0777500884  0.1144203604 -8.201987e-02
#>   [96,]  0.233089665 -0.1185246196 -0.2227373588  0.1158359163  3.163908e-02
#>   [97,] -0.235914116 -0.0872562720  0.1003636033  0.1336223890 -9.587557e-02
#>   [98,]  0.167519158  0.1023879834 -0.0132203565  0.0309516046 -1.766326e-02
#>   [99,]  0.021517058 -0.0151734950 -0.0924849608  0.0614425357  2.965564e-01
#>  [100,] -0.051733088 -0.1831777984 -0.1022405821  0.0628142978  6.648866e-03
#>  [ reached getOption("max.print") -- omitted 900 rows ]
#> 
#> $v
#>             [,1]         [,2]          [,3]          [,4]         [,5]
#>   [1,] 0.2149260 -0.076190416 -0.0822264127 -0.2680622085 -0.088755782
#>   [2,] 0.2974099 -0.232937362 -0.0901852067 -0.0483096043 -0.052899648
#>   [3,] 0.3803527  0.489017270  0.5391790434 -0.0310228671  0.004716606
#>   [4,] 0.2849800  0.400455240  0.1658514778 -0.0294860829  0.516942557
#>   [5,] 0.4885513  0.677955132  0.6125165970 -1.1562645144 -0.155175908
#>   [6,] 0.4722826  0.026631083 -0.2578209026 -0.4143583341 -0.466522173
#>   [7,] 0.2505574  0.064087150  0.0925318622  0.2576670305  0.067305827
#>   [8,] 0.2253700 -0.059300085  0.0150463412 -0.0335798270  0.177201830
#>   [9,] 0.3175433  0.399589016  0.0537158239 -0.2465391217  0.069136695
#>  [10,] 0.5258952  0.962911199 -0.8886627745  0.3508963388  0.078743600
#>  [11,] 0.2303544 -0.065997430  0.1947274535 -0.2671454711  0.060202358
#>  [12,] 0.3282651 -0.160493664  0.1385537558 -0.2120140026  0.509570564
#>  [13,] 0.3228640 -0.306730119  0.1888055571  0.4611237092  0.365528059
#>  [14,] 0.2342243 -0.185433574 -0.2301694613 -0.0001633888  0.227240111
#>  [15,] 0.2014615 -0.180938351  0.0900545166 -0.0856514023 -0.108630519
#>  [16,] 0.2572740 -0.067160079  0.0663337931  0.1048991230 -0.038117931
#>  [17,] 0.3856626 -0.083690259  0.3803492442  0.6825630433 -0.119483416
#>  [18,] 0.3021844  0.034948908 -0.2266511422 -0.0474070970  0.084740279
#>  [19,] 0.2851221 -0.098416965  0.1545435813 -0.0923970828  0.254524320
#>  [20,] 0.5328422 -1.949104402 -0.9771492112 -0.0619439768  0.369542679
#>  [21,] 0.3222199  0.192036181 -0.1492608182 -0.1117176473  0.172440298
#>  [22,] 0.1540626 -0.080286063 -0.0018381742 -0.0773085134  0.190073355
#>  [23,] 0.2874883 -0.020398321 -0.0655621858  0.0510557254 -0.281658075
#>  [24,] 0.2739418  0.035421543  0.0900500387  0.2209373124  0.001857070
#>  [25,] 0.4008466  0.470269547 -0.0411605156 -1.0289755144  0.537932658
#>  [26,] 0.3837962 -0.462649264  0.0422903344  0.0878602156  0.455321338
#>  [27,] 0.4235156 -0.602883724  0.5915828841  0.3673574262 -0.556106952
#>  [28,] 0.2568168  0.003390262  0.1157055351  0.0343647311 -0.052906957
#>  [29,] 0.3607412  0.769415099 -0.3902604980  0.6635494374 -0.102940001
#>  [30,] 0.2475474 -0.483461138 -0.1607114216 -0.2968399920 -0.354084025
#>  [31,] 0.3075315  0.029731818  0.0576052587  0.3089014205 -0.429483726
#>  [32,] 0.2188245 -0.209851108  0.2381509207  0.0389135957  0.020540955
#>  [33,] 0.3533810 -0.056417296  0.2064956405 -0.4435013706  0.037010439
#>  [34,] 0.1998890 -0.043688528  0.1664296844  0.0206046153  0.257260288
#>  [35,] 0.2004848 -0.130836632  0.0711531102 -0.0780530306 -0.052179616
#>  [36,] 0.2482743 -0.162133436 -0.0314601953 -0.0970668644  0.062552320
#>  [37,] 0.3794031 -0.171107197 -0.1409103124  0.2956899868  1.107064676
#>  [38,] 0.3068617 -0.008584008 -0.2006073302  0.0916998906  0.326934694
#>  [39,] 0.3774921  0.297789679 -0.4535301836  0.0500693418  0.585463349
#>  [40,] 0.2820791 -0.135704393  0.5190805015  0.0709882989  0.105457133
#>  [41,] 0.2773272 -0.371826026 -0.0336403497 -0.1442956766 -0.048735280
#>  [42,] 0.2947680  0.039454913 -0.1330100071  0.0981748056 -0.197113608
#>  [43,] 0.2237271 -0.146204894 -0.0123229801 -0.0722456542  0.051779133
#>  [44,] 0.4893929  0.041773064 -0.4866427394  0.3658038681  0.693396063
#>  [45,] 0.3617168 -0.567190372  0.9087851351 -0.0545295751  0.211781264
#>  [46,] 0.2503159 -0.186543493  0.0620409823 -0.0568035794 -0.092979131
#>  [47,] 0.2323670 -0.098880133 -0.0350956006 -0.0345656037  0.132960984
#>  [48,] 0.2834040  0.134723128 -0.2263320209 -0.4001687401  0.359097062
#>  [49,] 0.2260726  0.123392451 -0.0943935892 -0.0521986671 -0.035178679
#>  [50,] 0.2670545 -0.308342775 -0.0008648042 -0.1166895752  0.072783302
#>  [51,] 0.2439850 -0.021424675 -0.1123268374 -0.1087985453  0.237570737
#>  [52,] 0.2974427 -0.074175177 -0.1260432002  0.1693843777  0.244866871
#>  [53,] 0.2007577 -0.118086624  0.3713457552 -0.0560206711 -0.197539814
#>  [54,] 0.3850171  0.133816261  0.2917843135  0.0132542783 -0.023005848
#>  [55,] 0.2666920 -0.115228898 -0.0359589458  0.3973397956 -0.175941945
#>  [56,] 0.5422125  0.103843196 -0.5977387652 -0.0642093520 -1.947392760
#>  [57,] 0.4237825  0.663122789 -0.4043623298 -0.5131672259 -0.013179763
#>  [58,] 0.3148849  0.185369973  0.0122641053  0.3429166455  0.084489146
#>  [59,] 0.2836933  0.035987587 -0.0782909331  0.0772479146 -0.154080314
#>  [60,] 0.3713090  0.145371071  0.1528781717 -0.1680665462  0.024712810
#>  [61,] 0.2825946 -0.110375344 -0.1301149892 -0.2375007506  0.009582661
#>  [62,] 0.3029739 -0.315281663  0.3716817926 -0.0428740086 -0.005890357
#>  [63,] 0.2113266  0.212236609  0.0770854037  0.3184069149 -0.142519887
#>  [64,] 0.1941621 -0.148110851  0.0209731956 -0.1705038062  0.186098778
#>  [65,] 0.2413661 -0.374593814 -0.0241057686 -0.0349413847 -0.011133682
#>  [66,] 0.3652099 -0.233862183 -0.3143100465 -0.2447641855  0.009260882
#>  [67,] 0.2280040  0.134207919 -0.1773819032 -0.1748581789  0.340656830
#>  [68,] 0.3756730  0.261653746  0.0385259025 -0.1414398182  0.215887496
#>  [69,] 0.2802568 -0.297344742 -0.0872736295 -0.2018010609  0.062441997
#>  [70,] 0.4792029  0.528826766  0.0080841026 -0.7257836954 -0.025143970
#>  [71,] 0.2677620  0.396922978 -0.0740489969  0.1718078696  0.295805542
#>  [72,] 0.3049306 -0.029236244 -0.2893005208 -0.1787351194 -0.128458190
#>  [73,] 0.4742746 -0.209666201 -0.0959889713  0.1239931896 -0.471218648
#>  [74,] 0.5117096  0.423306042  1.6612708828  0.8917260353  0.448592988
#>  [75,] 0.2981851 -0.132351141 -0.4053110756  0.2350450072  0.284131203
#>  [76,] 0.3732082 -0.011811016 -0.0659619601 -0.6645208779  0.158884685
#>  [77,] 0.3351017  0.068172313  0.2240278277  0.0473466200 -0.296940247
#>  [78,] 0.2840126 -0.476961395 -0.2619424656 -0.0046694786  0.206718753
#>  [79,] 0.4099535 -0.446932996  0.7843617008  1.1441859323 -0.144452308
#>  [80,] 0.4414757 -0.182042783  0.5907650958 -0.5053725611 -0.315021549
#>  [81,] 0.3489320  0.003042576 -0.1442799473 -0.0411653764  0.187536740
#>  [82,] 0.4525799  0.246623366 -0.1751828678  0.7654963894 -0.865706229
#>  [83,] 0.2656481 -0.400646732 -0.1181721326 -0.0762009136  0.034375926
#>  [84,] 0.2830458  0.157693752 -0.1909134851  0.0782065966  0.153281751
#>  [85,] 0.1930024 -0.182612498  0.1924962674 -0.1471814320  0.083300173
#>  [86,] 0.2924796 -0.242241368  0.5356802558 -0.4947953212  0.446963949
#>  [87,] 0.2570445 -0.187105456  0.0586041631 -0.0842090344 -0.131231020
#>  [88,] 0.2804309  0.158442242  0.2147863508 -0.1679680407  0.265124886
#>  [89,] 0.3057172  0.126014457  0.4608058605 -0.4738780869 -0.229220991
#>  [90,] 0.2973654 -0.233879948  0.0429093674 -0.2162018343 -0.559440661
#>  [91,] 0.4056711  0.216237703  0.6641400556 -0.2061471000 -0.011149722
#>  [92,] 0.3025589 -0.128097667  0.4446207105 -0.2293002293  0.011846570
#>  [93,] 0.5172331  0.572953234 -0.7714388093  0.9818085601  0.192697226
#>  [94,] 0.2785030 -0.404921073 -0.4513148827 -0.1058019288  0.043498628
#>  [95,] 0.1972177 -0.120601454  0.1169447614  0.0823344899  0.255632481
#>  [96,] 0.3859856 -0.462559975  0.1431492172 -0.4855087484 -0.346314778
#>  [97,] 0.4239506 -0.234623366 -0.0163490644 -0.6229517371  0.021633756
#>  [98,] 0.2754687  0.298160466  0.0735441924 -0.2754830599 -0.011155356
#>  [99,] 0.2839010 -0.383913076  0.0116048572  0.1047186716  0.046960720
#> [100,] 0.3702165 -0.273941741  0.4472915457 -0.2277925109 -0.233898219
#>                 [,6]         [,7]         [,8]         [,9]        [,10]
#>   [1,]  0.2547440286  0.168580889  0.238120369 -0.178895832 -0.038999015
#>   [2,] -0.0164694431 -0.079552584 -0.190327378  0.145703678  0.336695347
#>   [3,]  0.3149674463 -0.159119998  0.311928987  0.150242263 -0.266908220
#>   [4,] -0.2733627187  0.160516283 -0.267054246 -0.486495219 -0.167115839
#>   [5,]  1.1960926641 -0.604500148 -0.942524266  0.078738985  0.277218956
#>   [6,]  0.4849638784  0.586423244  0.024577359 -0.471299361 -0.228243604
#>   [7,]  0.2602688165 -0.565803266  0.186190125  0.186915626 -0.049198341
#>   [8,] -0.0314835697 -0.124186011  0.241863182 -0.280811722 -0.100573117
#>   [9,]  0.4107510602 -0.379783993 -0.127956552  0.197622360  0.584510871
#>  [10,]  0.0365730128  0.176126557  0.108033824 -0.362374070  0.097757108
#>  [11,] -0.2974601837 -0.198393453  0.202273877 -0.007740457 -0.117793583
#>  [12,] -0.2062595940  0.163015120  0.047647233 -0.181176253  0.244200423
#>  [13,]  0.3177397804 -0.001065707  0.174220431  0.200680911 -0.266671030
#>  [14,] -0.0307815163  0.218336491 -0.284536782 -0.158758656 -0.229542818
#>  [15,] -0.1538896826 -0.179274634  0.103436551  0.273090505 -0.238357492
#>  [16,]  0.0609852669 -0.281550116  0.298061968 -0.080507801  0.008839671
#>  [17,] -0.2594970515 -0.275185404  0.574175116 -0.142554181  0.362411750
#>  [18,] -0.4702621745 -0.076632518  0.365183457  0.103563270 -0.046762562
#>  [19,] -0.1670904550  0.071321475  0.150762397 -0.206908581  0.231860148
#>  [20,]  0.7595153547  0.287018207 -0.376119394  0.898159118  0.971702426
#>  [21,] -0.0112900200 -0.500625069  0.448005550 -0.591598877  0.108089440
#>  [22,] -0.2157457153  0.102106354  0.029750065 -0.176875075 -0.156582849
#>  [23,] -0.0361053609  0.163938825  0.304640298 -0.072222067  0.108088967
#>  [24,] -0.1711443390 -0.232283941  0.023201688 -0.212317961  0.437878253
#>  [25,]  0.2394987388 -0.082703160  0.719735215 -0.335206216  0.603122823
#>  [26,] -0.1676885446 -0.347194001 -0.278206789 -0.476664067 -0.021677305
#>  [27,] -0.1447884096  0.244841883 -0.004201765 -1.267264098  0.298086623
#>  [28,]  0.0689683297 -0.181751316  0.116788936 -0.105583195  0.053546737
#>  [29,]  0.0336695323 -0.227913020  0.167505585  0.746992221 -0.038482186
#>  [30,] -0.2595428668  0.374450384  0.011246945  0.129106641 -0.332461203
#>  [31,] -0.1029592202 -0.307485506 -0.322067741  0.223347247 -0.411762696
#>  [32,] -0.1860044600 -0.004671251  0.207380768 -0.311526677 -0.193561335
#>  [33,]  0.3539427930 -0.412844422 -0.644798642 -0.288636145  0.014714085
#>  [34,] -0.1368834375 -0.072060078  0.062925977 -0.124409054 -0.053840953
#>  [35,] -0.3776745738  0.007010752  0.283885004 -0.059463311 -0.158191376
#>  [36,] -0.0961602521 -0.118665908  0.167970399 -0.118466411 -0.218569160
#>  [37,]  0.0374307193 -0.036637713  0.378914472 -0.520700884 -0.637846004
#>  [38,]  0.4980481581  0.134463430  0.139236384 -0.480705127 -1.066487750
#>  [39,] -0.6832876911 -0.289318188  0.173715387 -0.238475216 -0.290694719
#>  [40,]  0.0289828001  0.040361844  0.179857022  0.076731262 -0.077058849
#>  [41,] -0.5220171478  0.071087116 -0.097549725  0.023060073 -0.214726073
#>  [42,]  0.3983257880  0.290219349 -0.262429721 -0.293749449 -0.351761845
#>  [43,]  0.0024515738 -0.142922097  0.051711640 -0.009982002 -0.072819497
#>  [44,] -0.5919924640 -0.231619309 -0.468293711 -0.572436096  0.992497128
#>  [45,]  0.8383392720  0.049944049  0.668682258 -0.147813152 -0.087509893
#>  [46,]  0.0496007839 -0.324037755  0.240942797 -0.090076234 -0.191135054
#>  [47,]  0.0070510247  0.339936240 -0.215660176 -0.202270043 -0.150606032
#>  [48,] -0.1939965206  0.334817856 -0.095900041  0.288311497 -0.258437472
#>  [49,]  0.0172618638 -0.176193502 -0.289336137  0.086308545 -0.125265960
#>  [50,] -0.2594380857 -0.061810135  0.188894283  0.412231821 -0.315673331
#>  [51,]  0.2592854332 -0.054411829  0.075324259  0.021315835  0.211293029
#>  [52,]  0.0449375164 -0.233382911 -0.031949867 -0.843878300  0.080491983
#>  [53,]  0.0874539944  0.116820712 -0.058167031  0.115272545 -0.380116057
#>  [54,] -0.2056009760 -0.432731728  0.038136142  0.232318697 -0.073828605
#>  [55,] -0.0355122828 -0.179369598 -0.228635531  0.012359695 -0.059577505
#>  [56,]  0.1532658687  0.306487067  0.770451072 -0.733076046  0.590510479
#>  [57,] -0.3928205541  0.292812326 -0.021120457 -0.160528553  0.135058144
#>  [58,]  0.4466652448  0.254694259 -0.250682967 -0.037018717 -0.611712455
#>  [59,] -0.1594395643  0.044090082 -0.173840979 -0.219341187  0.190444076
#>  [60,]  0.1817297170  0.236726281  0.337898608  0.331766578  0.076412823
#>  [61,]  0.2727139418 -0.012716707  0.106912796  0.024947834 -0.032353838
#>  [62,] -0.6897258823 -0.324831717  0.108435400  0.035004568 -0.291684712
#>  [63,] -0.1770494839  0.055883012 -0.070065786 -0.087216390 -0.078540769
#>  [64,] -0.0631795611 -0.096487292  0.058892649  0.086868857  0.228468395
#>  [65,] -0.3705698490 -0.009465416  0.204554390 -0.097344226 -0.109352641
#>  [66,] -0.7164747403  0.094197103 -0.100050951  0.036431516 -0.227853278
#>  [67,]  0.0817635333 -0.018733244  0.428717114  0.244464277 -0.138709386
#>  [68,]  0.2724349460  0.141130282 -0.075127829  0.039483747  0.149668453
#>  [69,] -0.0659565565 -0.202052472  0.171284135  0.185663837  0.065886137
#>  [70,] -0.4237009593 -0.411551633 -0.830976686  0.399866542  0.140388109
#>  [71,]  0.3617910991  0.369864221 -0.200138439 -0.019184583 -0.363277377
#>  [72,]  0.0009644288  0.317020790  0.020923623 -0.084949793 -0.090057873
#>  [73,] -0.1565175605 -2.187194337 -0.323979144  0.051364162 -0.191720340
#>  [74,] -0.2147188097  0.968993066 -0.394521616  0.447211449  0.517589343
#>  [75,]  0.1176618066 -0.181010845  0.346515551  0.043034665 -0.049500501
#>  [76,]  0.2957110099  0.207529294  0.013925144  0.427481222 -0.505042521
#>  [77,] -0.4592205233  0.455723260 -0.308032753 -0.314869650 -0.452676346
#>  [78,]  0.0602985740 -0.090332568 -0.460301454  0.100296124 -0.157818881
#>  [79,]  0.4155500305 -0.492572007 -0.321668655 -0.182259051 -0.034729687
#>  [80,] -0.9660313344  0.092002950 -0.501336661  0.305617663 -0.166487994
#>  [81,] -0.1240598016  0.024665103 -0.885718585 -0.399502010 -0.168867232
#>  [82,] -0.0335121833  0.519769689 -0.773172617  0.582306358  0.031319478
#>  [83,] -0.0600854641 -0.268652726 -0.048556436  0.183298659 -0.257411071
#>  [84,]  0.4118478557 -0.076813221  0.171620384 -0.522752493 -0.388878617
#>  [85,]  0.1004374689  0.095970843  0.133387604  0.041416046 -0.292599274
#>  [86,] -0.1331831871 -0.079646144  0.758173477  0.200967719  0.099787271
#>  [87,] -0.0423677222  0.268038429 -0.071506221  0.266059779 -0.448278787
#>  [88,] -0.5055875092  0.308970888 -0.382332009 -0.134452903  0.165640712
#>  [89,] -0.3869736138 -0.165452687  0.207904279  0.295123996 -0.195371633
#>  [90,] -0.2183914331 -0.298787367  0.448240324 -0.133528592 -0.357831679
#>  [91,]  0.3258080498  0.434638587  0.541499734  0.133174438  0.726353936
#>  [92,] -0.1009565750 -0.361110662  0.453477377 -0.302787257 -0.092732110
#>  [93,] -0.2091130163 -0.062193785  0.854567797  1.252197921  0.237930779
#>  [94,]  0.4531727762  0.234990628 -0.197789206 -0.149451490 -0.063951215
#>  [95,] -0.0779829632  0.024509581  0.009517371  0.115410983 -0.026071212
#>  [96,] -0.2259513981  0.443588806  0.336673079  0.634519716 -0.386170314
#>  [97,] -0.9963902668  0.161206413  0.071057732 -0.105762544  0.273122691
#>  [98,]  0.0353323918 -0.059380730  0.127655377  0.208348778 -0.056791752
#>  [99,] -0.2968287439 -0.012681463 -0.206885586 -0.251720110  0.556237895
#> [100,] -0.5021861944 -0.247749187  0.480515033  0.131095213  0.067244273
#> 
#> $penal_lik
#> [1] -100578.5
#>